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Telomeres as protective "caps" on the tips of eukaryotic chromosomes. How telomerase extends telomeres.Telomeres are really conserved tandem nucleotide repeats that incorporate proximal double-stranded and distal one-stranded regions that in intricate with shelterin proteins pay for defense at chromosomal finishes to take care of genomic integrity.
Considering that the discovery of telomerase, it has grown to be obvious that this material plays a vital role while in the regulation of telomere length. In general, telomeres are likely to shorten in cells without telomerase above time, and cells may possibly cease dividing and develop into senescent after their telomeres shorten under a vital le